Plurisin#1
WebAug 5, 2014 · following exposure to PluriSIn#1, indicating that PluriSIn#2 works through a different mechanism of action (Fig. 1D). We therefore applied an unbiased toxicogenomic approach, in order to detect the gene expression changes induced by the compound. Following a 12-hour exposure of undifferentiated hPSCs to PluriSIn#2 (20 mm) or to control WebThis product is manufactured by BioVision, an Abcam company and was previously called 2471 PluriSIn 1. 2471-50 is the same size as the 50 mg size of ab145629. CAS Number. 91396-88-2 . Chemical structure. Properties. Chemical name. N'-Phenylpyridine-4-carbohydrazide. Molecular weight. 213.24. Molecular formula. C 12 H 11 N 3 O. …
Plurisin#1
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WebNSC 14613 is a pluripotent cell-specific inhibitor (PluriSIn) that selectively eliminates human pluripotent stem cells (hPSCs) leaving a large array of progenitor and differentiated cells unaffected. Among 15 identified PluriSIns, NSC 14613 (also known as PluriSIn #1) is a derivative of N-acyl phenylhydrazine that shares a common structure moiety, … WebFeb 7, 2013 · PluriSIn #1 was also cytotoxic to mouse blastocysts, indicating that the dependence on oleate is inherent to the pluripotent state. Finally, application of PluriSIn …
WebNov 11, 2024 · Visit ChemicalBook To find more PluriSln 1(91396-88-2) information like chemical properties,Structure,melting point,boiling point,density,molecular … WebMay 5, 2014 · In a series of experiments, both in cell culture and in mice, they demonstrated that PluriSin#1 does remove the tumorigenic iPS cells. Further they showed that treated iPS cells could be given to mice hearts without causing tumors. The breakthrough by Zhang et al. needs to be repeated for human iPS cells, but it makes stem cells for heart ...
Web在15种已确认的PluriSIn中，NSC 14613（亦称PluriSIn＃1）是一种N-酰基苯肼的衍生物，与其它9种PluriSIn共享常见的苯基肼（PH-N[H，C]-NH）结构部分。 NSC14613也是 … WebBiological Activity. PluriSln 1 is a stearoyl-CoA desaturase 1 (SCD1) inhibitor. Used to selectively eliminate undifferentiated human pluripotent stem cells (hPSCs) from culture; …
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WebLearn more about PluriSIn 1. We enable science by offering product choice, services, process excellence and our people make it happen. regina blitz xl kitchen rollWeb72822 72824 - PluriSIn-1 Revision Number 2 Chemical name CAS No. Weight-% N'-phenylpyridine-4-carbohydrazide 91396-88-2 100 *The exact percentage (concentration) … regina bed bath and beyondWebsensitive to PluriSIn#1, but 1 week of RA- have recently identified several small mole- Interestingly, while the immortalized fibro- induced differentiation rendered them com- cules termed pluripotent-specific inhibitors blasts exhibited a very weak response, the pletely resistant to the molecule (Figure 1E (PluriSIns) that selectively target undif- transformed … regina garner school boardWebPluriSln 1 is a stearoyl-CoA desaturase 1 (SCD1) inhibitor. Used to selectively eliminate undifferentiated human pluripotent stem cells (hPSCs) from culture; induces ER stress, … regina olson hughes asllafayette vs holy cross basketball predictionWebPluriSIn 1 is a selective inhibitor of steroyl-CoA desaturase 1 (SCD1), the key enzyme in oleic acid biosynthesis. PluriSIn 1, induces ER stress, protein synthesis attenuation, and … lafayette vs umbc predictionWebJan 10, 2013 · PluriSIn #1 was also cytotoxic to mouse blastocysts, indicating that the dependence on oleate is inherent to the pluripotent state. Finally, application of PluriSIn #1 prevented teratoma formation from tumorigenic undifferentiated cells. These findings should increase the safety of hPSC-based treatments. lafayette vs american coney island